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Emerging data in clinical and preclinical studies suggests the adverse and efficacious effects of these pharmacotherapies can be dissociated, and that GIPR agonism improves the GI AE profile of GLP-1R and dual incretin receptor agonists
Yamamoto, T., et al
Those at risk for dehydration, with pre-existing kidney disease, or who are unable to maintain consistent exercise intensity should avoid this combination without explicit provider oversight
When is constipation considered dangerous
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